Organic sulfuric acids and derivatives
Sigma Aldrich Fine Chemicals Biosciences Sodium cyclamate European Pharmacopoeia (EP) Reference Standard | 139-05-9 | MFCD00003827 |
Sodium cyclamate European Pharmacopoeia (EP) Reference Standard | Mol Wt: 201.22 | 139-05-9 | MFCD00003827 |
Medchemexpress LLC Lobeglitazone (sulfate) | 763108-62-9 | 99.6% | 578.61 | 5 MG
Lobeglitazone sulfate is a novel thiazolidinedione, functioning as an orally active agonist for PPAR with EC50 values of 137.4 nM for PPARγ and 546.3 nM for PPARα. It acts as an inhibitor for the ERK/JNK/Smad/NF-κB signaling pathway, demonstrating anti-inflammatory, anti-diabetic, anti-fibrotic, and anti-atherosclerotic properties.
- Functions as an orally active agonist for PPAR
- Inhibits ERK/JNK/Smad/NF-κB signaling pathway
- Exhibits anti-inflammatory properties
- Exhibits anti-diabetic properties
- Exhibits anti-fibrotic properties
- Exhibits anti-atherosclerotic properties
- Increases glucose uptake in 3T3-L1 adipocytes and L6 muscle cells
- Inhibits NO generation and pro-inflammatory cytokine expression
Medchemexpress LLC Sodium laureth sulfate | 9004-82-4 | 70% | (C2H4O)nC12H26O4S.Na | 5 G
Sodium laureth sulfate is an anionic active agent known for its excellent decontamination, emulsification, dispersion, wetting, and antifungal properties. It is commonly used in various applications where these properties are beneficial.
- Excellent decontamination and emulsification
- Effective dispersion and wetting capabilities
- Possesses antifungal properties
- Suitable for a wide range of applications requiring anionic active agents
Sigma Aldrich Fine Chemicals Biosciences Sodium cyclamate United States Pharmacopeia (USP) Reference Standard | 139-05-9 | MFCD00003827 | 200MG
Sodium cyclamate United States Pharmacopeia (USP) Reference Standard | Mol Wt: 201.22 | 139-05-9 | MFCD00003827 | 200MG
Medchemexpress LLC Sodium laureth sulfate | 9004-82-4 | 70% | (C2H4O)nC12H26O4S.Na | 25 G
Sodium laureth sulfate (70% in water) is an anionic active agent that exhibits excellent decontamination, emulsification, dispersion, wetting, and antifungal properties. It is intended for research use only.
- Anionic active agent
- Exhibits decontamination properties
- Exhibits emulsification properties
- Exhibits dispersion properties
- Exhibits wetting properties
- Provides antifungal properties
- Enhances inactivation efficiency against *S. cerevisiae* cells
- Disrupts membrane integrity in *S. cerevisiae* cells
- Increases cell membrane permeability in *S. cerevisiae* cells
- Elevates lysosomal enzyme activities in guinea pigs
![Alkali Scientific 3 Indoxyl β D Glucoside [IBDG] [3 Indoxyl β D Glucopyranoside], 10 G](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000659598.jpg-250.jpg)
Alkali Scientific 3 Indoxyl β D Glucoside [IBDG] [3 Indoxyl β D Glucopyranoside], 10 G
3-Indoxyl β-D-Glucoside (IBDG) is a highly sensitive chromogenic substrate used for the detection of β-glucosidase activity in biochemical assays. The hydrolysis of IBDG by β-glucosidase results in the production of an indigo-colored compound, providing a visual indicator of enzyme activity. The 10g quantity is ideal for large-scale experiments or long-term studies. IBDG is commonly used in molecular biology, microbiology, and biochemical research to detect and quantify β-glucosidase activity in various organisms and samples. This reagent offers a convenient, easy-to-interpret method for screening enzyme activity, studying gene expression systems, and analyzing enzymatic reactions in a wide range of applications.
![Alkali Scientific 3 Indoxyl β D Glucoside [IBDG] [3 Indoxyl β D Glucopyranoside], 100 Mg](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000659681.jpg-250.jpg)
Alkali Scientific 3 Indoxyl β D Glucoside [IBDG] [3 Indoxyl β D Glucopyranoside], 100 Mg
3-Indoxyl β-D-Glucoside (IBDG) is a chromogenic substrate used for the detection of β-glucosidase activity in biochemical assays. Upon hydrolysis by β-glucosidase, the substrate produces an indigo-colored product, which is useful for visualizing enzyme activity in bacterial colonies or cell cultures. The 100mg format is ideal for smaller-scale applications and routine laboratory experiments. IBDG is widely used in molecular biology, microbiology, and genetic research to monitor gene expression, screen for β-glucosidase activity, and study enzyme function. This reagent offers a clear, colorimetric result that is easy to interpret, providing researchers with an efficient tool for enzyme assays and gene function analysis.
Cayman Chemical Indoxyl SulfatepotasIum sa 1g
A uremic toxin and metabolite of tryptophan; activates AhR in HepG2 40/6 hepatoma cells (EC50 = 12.1 nM in a reporter assay); inhibits OAT1 and OAT3 (Kis = 34.2 and 74.4 µM, respectively for the rat transporters) in S2 proximal tubule cells; increases superoxide anion and nitric oxide levels in isolated human mononuclear blood cells at 0.2 and 1 mM; increases serum creatinine and BUN levels in the 5/6 nephrectomized rat model of chronic renal failure at 50 mg/kg
Cayman Chemical Indoxyl Sulfate potassium sa
A uremic toxin and metabolite of tryptophan; activates AhR in HepG2 40/6 hepatoma cells (EC50 = 12.1 nM in a reporter assay); inhibits OAT1 and OAT3 (Kis = 34.2 and 74.4 µM, respectively for the rat transporters) in S2 proximal tubule cells; increases superoxide anion and nitric oxide levels in isolated human mononuclear blood cells at 0.2 and 1 mM; increases serum creatinine and BUN levels in the 5/6 nephrectomized rat model of chronic renal failure at 50 mg/kg
![Alkali Scientific 3 Indoxyl β D Glucoside [IBDG] [3 Indoxyl β D Glucopyranoside], 500 Mg](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000659557.jpg-250.jpg)
Alkali Scientific 3 Indoxyl β D Glucoside [IBDG] [3 Indoxyl β D Glucopyranoside], 500 Mg
3-Indoxyl β-D-Glucoside (IBDG) is a sensitive chromogenic substrate used for detecting β-glucosidase activity in biochemical assays. This reagent produces a distinctive indigo color when hydrolyzed by β-glucosidase, providing a visual indicator of enzyme activity. The 500mg quantity is ideal for larger experiments, high-throughput screening, or long-term studies. IBDG is widely used in microbiology and molecular biology for monitoring enzyme activity, conducting reporter assays, and studying gene expression systems. It offers an easy-to-use, reliable method for detecting β-glucosidase activity in cultured cells, bacterial colonies, and other biological samples.
Cambridge Isotope Laboratories INDOXYL SULFATE, POTASSIUM SALT (13C6, 99%) CHEMICAL PURITY 95%, 1 MG
INDOXYL SULFATE, POTASSIUM SALT (13C6, 99%) CHEMICAL PURITY 95%, 1 MG
Medchemexpress LLC Axelopran sulfate | 949904-50-1 | 555.68 g/mol | C26H41N3O8S | 10 MG
Axelopran sulfate is the sulfate salt of axelopran, an opioid receptor antagonist used in research to profile μ, δ, and κ opioid receptors. It is supplied for laboratory research, is highly soluble in DMSO, and has reported pKi values of 9.8 (human μ), 8.8 (human δ), and 9.9 (guinea pig κ).
- Sulfate salt form suitable for laboratory research.
- High reported affinity for opioid receptors (pKi 9.8-9.9).
- Soluble in DMSO: ≥ 100 mg/mL.
- Storage: 4°C sealed; in solvent -80°C (6 months), -20°C (1 month).
- Intended for in vitro and preclinical opioid receptor pharmacology studies.
Medchemexpress LLC Dermatan (sulphate sodium) | 54328-33-5 | 5 MG
Dermatan (sulphate sodium) | 54328-33-5 | 5 MG
Medchemexpress LLC Vindesine sulfate | 59917-39-4 | 99.17% | 100 MG
Vindesine sulfate is a potent tubulin inhibitor with a Ki of 0.110 μM. It exhibits anti-proliferation effects in vitro and antitumor effects in vivo. It is a white to off-white solid.
- Potent tubulin inhibitor
- Anti-proliferation effects in vitro
- Antitumor effects in vivo
- Solid appearance
- White to off-white color
- Store at -20°C, sealed, and away from moisture
Medchemexpress LLC p-Cresyl sulfate | 3233-58-7 | 99.98% | 188.20 | 25 MG
p-Cresyl sulfate (p-Tolyl sulfate) is a uremic toxin that can cause renal damage and dysfunction. It demonstrates antiproliferation activity, increases the protein expression of HIF-1α and VHL, and decreases the protein expression of HIF-2α. Additionally, p-Cresyl sulfate induces epithelial-mesenchymal transition (EMT) and activates the JNK and p38 MAPK signaling pathways.
- Is a uremic toxin.
- Can cause renal damage and dysfunction.
- Shows antiproliferation activity.
- Increases the protein expression of HIF-1α and VHL.
- Decreases the protein expression of HIF-2α.
- Induces epithelial-mesenchymal transition (EMT).
- Activates the JNK and p38 MAPK signaling pathways.
- Inhibits lipogenesis and increases lipolysis in adipocytes in 3T3-L1 cells.
- Induces osteoblast dysfunction through activating JNK and p38 MAPK pathways.
- Induces ROS production in primary osteoblastic cells.